CD154 blockade results in transient reduction in Theiler's murine encephalomyelitis virus-induced demyelinating disease.
نویسندگان
چکیده
Transient CD154 blockade at the onset of Theiler's murine encephalomyelitis virus-induced demyelinating disease ameliorated disease progression for 80 days, reduced immune cell infiltration, and transiently increased viral loads in the central nervous system. Peripheral antiviral and autoimmune T-cell responses were normal, and disease severity returned to control levels by day 120.
منابع مشابه
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ورودعنوان ژورنال:
- Journal of virology
دوره 77 3 شماره
صفحات -
تاریخ انتشار 2003